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In contrast, while the dose-response relationship between -cell responsiveness to glucose (expressed as the slope of the linear relation between insulin secretion rate and the glucose concentration) and GLP-1 levels in circulation is partially impaired a phenomenon referred as GLP-1 resistance (62) a therapeutic infusion of GLP-1 at a pharmacological dose can restore -cell insulin secretion responsiveness to glucose levels comparable to those observed in nondiabetic individuals (62)
O., Hassan, G
10.1210/en.2003-0805 99 KempurajD.SelvakumarG
This reduction was driven primarily by a 39% decrease in non-fatal stroke and a 26% decrease in non-fatal myocardial infarction (the latter not statistically significant on its own)
Selenium treatment in autoimmune thyroiditis: 9-month follow-up with variable doses
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