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In particular, signals from the gut can activate specialized neurons of the arcuate nucleus (ARC) that regulate energy and glucose homeostasis, including agouti-related peptide/neuropeptide Y orexigenic neurons and pro-opiomelanocortin/cocaine and amphetamine-regulated transcript anorexigenic neurons 22,33,34,35

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But before the celebration begins, the safety data deserves equal scrutiny

Its ability to induce substantial and sustained weight loss, coupled with its safety profile, makes it a promising option for individuals struggling with obesity

Both substances affect the gastrointestinal system, and alcohol's calorie content can undermine weight loss goals