Maturation of red blood cells from the immature megaloblasts produced in bone marrow is dependent on Vitamin B12, which is a precursor for co-enzyme B12 involved in important enzyme reactions in the production of components of folic acid, which in turn is essential for DNA synthesis
Most patients report minimal discomfort during the treatment
Bondad N, Boostani R, Barri A, Elyasi S, Allahyari A
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