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Thymosin 4 is a 43-amino-acid polypeptide of approximately 5 kDa

There are several mechanisms: receptor-mediated transport, EVs express a variety of receptors and ligands on the surface, which can bind to the receptors on the surface of BBB endothelial cells, triggering endocytosis, thus realizing transmembrane transport (133)

Tian Y, Russo RM, Li Y, Karmakar M, Liu B, Puskarich MA, et al

Ibuprofen: The Peripheral Defender Ibuprofen belongs to the Non-Steroidal Anti-Inflammatory Drug (NSAID) class

It has been found to exert a wide array of beneficial effects, including anti-inflammatory properties and the ability to promote angiogenesis (the formation of new blood vessels), which is crucial for tissue repair and regeneration