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It should be noted that the musculoskeletal evidence base remains preclinical, a 2025 scoping review by McGuire and colleagues in Current Reviews in Musculoskeletal Medicine found no adequately powered randomised controlled trials

This reaction converts H 2 O 2 and GSH into water and GSSG, thereby reducing ROS-induced cellular damage [35]

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2 Safety and Side Effects IV Glutathione is generally well-tolerated when administered under medical supervision