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Additionally, CHAC1 downregulation results in increased levels of ferroptosis inhibitors such as GPX4 and SLC7A11, underscoring its pivotal role in controlling ferroptosis and its potential as a therapeutic target in bladder cancer (Yu et al., 2024)
Rajanahally S, Raheem O, Rogers M, et al
P., Feierman, D., Cederbaum, A
Ishibashi M, Akazawa S, Sakamaki H, Matsumoto K, Yamasaki H, Yamaguchi Y, Goto S, Urata Y, Kondo T, Nagataki S: Oxygen-induced embryopathy and the significance of glutathione-dependent antioxidant system in the rat embryo during early organogenesis
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