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At baseline, mean age was 46 years (range 18-86), 74% were female, 75% were White, 13% were Asian and 6% were Black or African American

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Beyond their insulinotropic effects, coordinated GLP-1R, GIPR, and GCGR signaling also influence lipid metabolism and energy expenditure by modulating hepatic lipid handling and adipose tissue function

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Puntarulo S, Cederbaum AI