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USA 112 , 1575515760 (2015)

Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell

Exercise can induce oxidative stress, which is a trigger for hemolytic anemia in people with G6PD deficiency ( However, studies in athletes suggest that oxidative stress brought about by exercise is not significantly higher in people with G6PD deficiency ( So, its likely safe for individuals with G6PD deficiency to use exercise to improve their quality of life ( Still, more studies on exercise in people with G6PD deficiency are needed

327 Additional sHSP family members, including HSBP6, HSBP7, HSBP8, and HSBP9, play important roles in mitigating polyQ-mediated toxicity in HD

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