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According to the drug's prescribing information, these potential risks are: An allergic reaction (hypersensitivity) Severe low blood sugar in people with type 2 diabetes, especially those taking insulin or sulfonylureas Complications related to diabetic retinopathy in those with type 2 diabetes Acute pancreatitis or gallbladder disease Acute kidney injury Increases in heart rate Suicidal ideation or behavior Lastly, Wegovy may increase the risk of certain thyroid tumors but this has only been observed in rodent studies
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They sit inside cells, bind ligands, and regulate the transcription of large gene programs governing lipid metabolism, glucose handling, and inflammation
The functionality of the GIPR/CRE Luciferase Reporter HEK293 Cell Line was validated in dose-response assays using the agonists gastric inhibitory peptide (GIP), Tirzepatide, and Retatrutide
