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The acute hemolysis, that is the only common clinical manifestation associated with pathogenic variants in the G6PD gene, can rapidly be compensated for and thus, may remain undetectable

Intraperitoneal injection of PMX500FI not only significantly reduced cell apoptosis in the photoreceptor layer of a mouse retinal detachment model and alleviated the inflammatory response accompanied by retinal detachment but also broadly protected the thickness of the outer nuclear layer, thereby maintaining the structural integrity and functional efficacy of the retina [322]

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Chronic stress: Elevated cortisol degrades the extracellular matrix around follicles and triggers inflammation, accelerating shedding