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Vehicle-control MIA mice that received intraventricular normal saline infusions did not have a significant change in sociability index scores, with pre-vehicle scores of 8.2 1.4 comparable to post-vehicle score of 5.2 1.7, p = 0.70 (Fig 2A)

A recent survey of 251 current and former users gives us a closer look at how these changes are shaping real experiences in 2025

10.1292/jvms.14-0633 20

These enzymes catalyze the ATP-dependent formation of a thioester bond between ubiquitin and the E1 active site, marking the first step in the ubiquitination cascade

Y., Bahar, I