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However, whether pharmacological inhibition of the enzyme could elevate oxyntomodulin levels sufficiently to contribute to the therapeutic effect of DPP-4 inhibitor therapy is not known

Glutathione exists in two primary states within the cell: Reduced glutathione (GSH): The active, antioxidant form Oxidized glutathione (GSSG): The spent form, converted back to GSH by the enzyme glutathione reductase using NADPH Under healthy physiological conditions, more than 98% of cellular glutathione exists in the reduced (active) form