Still, they are also a result of mitochondrial dysfunction, which occurs when mitochondria lose the protection of GSH, free radicals attack the mitochondria, and cellular energy decreases.8 Autoimmune conditions like multiple sclerosis, Crohns disease, rheumatoid arthritis, diabetes, Lyme disease, heavy metal load, organotoxins, and more all have mitochondrial dysfunction, low levels of GSH, and profound fatigue
doi: 10.1016/S0140-6736(95)91084-0 48 DEliosMMBergmanMPAzzurriAAmedeiABenagianoMDe PontJJet al
Sandler 1990
In this regard, in healthy subjects, having a mixed meal, a combination of protein, carbohydrates, and fat, followed by a higher energy expenditure, prolonged the rate of gastric emptying and resulted in lower glycemia compared with a meal of carbohydrates alone [14]