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Lunetta KL, D'Agostino RB, Karasik D, Benjamin EJ, Guo CY, Govindaraju R, Kiel DP, Kelly-Hayes M, Massaro JM, Pencina MJ, Seshadri S, Murabito JM: Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study
One of the most important risk factors for glaucoma is elevated intraocular pressure (IOP), which promotes mechanical stress in RGCs and the lamina cribrosa, blockading axonal transport and causing axonal degeneration 3,4