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This receptor activation results in: Rapid, pulsatile increases in GH secretion Amplification of sleep-related GH peaks Synergistic interaction with Growth Hormone-Releasing Hormone (GHRH) pathways The end result is elevated circulating levels of GH and IGF-1 , which support muscle growth, fat metabolism, and tissue repair
Pharmacol Rev 50:335356 Aoyama K, Suh SW, Hamby AM, Liu JL, Chan WY, Chen YM, Swanson RA (2006) Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
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Rice, D
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