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Co-crystal structures of GSTO1 with our inhibitors demonstrate covalent binding to the active site cysteine
Doedens L et al
BioMed Res Internat
PubMed laboratory research record [PMID: 24497363] PubMed record related to this compound for laboratory literature review
Sample preparation was conducted using a proprietary (Metabolon, Durham, North Carolina, USA) series of organic and aqueous extractions to remove the protein fraction while allowing maximum recovery of small molecules
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