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Fourth, sKlotho is also produced by extra-renal organs (Lim et al., 2015
Although we cannot prove the direct pathophysiological effects of GLP1-RAs on FIBO in this particular case, GLP1-RAs have been reported to be one of the underlying risks of bowel obstruction based on epidemiological and basic research evidence
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Your doctor will typically: Check blood tests (potassium, kidney function) before starting and periodically during treatment Monitor your blood pressure regularly Adjust either medications dose based on your response and any side effects Possibly increase monitoring frequency if you have heart failure, kidney disease, or take other medications affecting potassium Take home message Mounjaro and spironolactone can be taken together safely, but this combination requires appropriate monitoring of potassium levels, kidney function, and blood pressure