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GLP-1 injections not only manage type 2 diabetes but also support weight loss through various mechanisms: Promoting Fullness: By stimulating receptors in the brain, GLP-1 injections enhance feelings of satiety and reduce appetite, leading to decreased food consumption

Fattah A et al

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This timeline matches B12 pharmacokinetics: intramuscular methylcobalamin reaches peak serum concentration at 8-12 hours, but tissue saturation (particularly in the liver and nervous system) occurs over 48-72 hours as the vitamin is transported into cells and converted to active coenzyme forms (Andrs et al., 2018)

Weight Rebound: Up to 70% regain weight after stopping, as drugs suppress appetite without fixing underlying metabolic issues