In recent years, 5Amino1MQ Peptide (abbreviated as 5Amino1MQ), a highly selective smallmolecule peptide inhibitor targeting nicotinamide Nmethyltransferase (NNMT), has exhibited broad application prospects and become a research hotspot in obesity and adipose tissue research due to its unique mechanism, favorable targeting ability, and safety
Encapsulation may also reduce compound degradation during storage, offering extended shelf life compared to reconstituted solutions
In addition, NNMTi promotes the secretion of antiinflammatory lipids (such as PAHSA) by adipocytes, further relieving adipose inflammation and improving metabolic function
Furthermore, it reduces hepatic gluconeogenesis by improving insulin resistance, further relieving liver fat accumulation
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