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Abstract The human gut microbiota is a complex, dynamic, and highly diverse community of microorganisms
Keratinocytes interact with immune cells recruited to the site of inflammation and increase the expression of adhesion molecules, which enables immune cells to adhere to the vascular endothelium ( According to the literature, oxidative and nitrosative stress plays a role in the progression of chronic spontaneous urticaria (CSU) ( Table 1 ) (164, 165)
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The honest caveat: most of this evidence is from cell and animal studies
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