Horvath O, Ordog K, Bruszt K, Kalman N, Kovacs D, Radnai B, et al
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Administering hepsin to wild-type mice increases APAP tolerance and downregulates GJ expression Considering the potential clinical and medical applications, we evaluated a therapeutic strategy involving the administration of hepsin to wild-type adult mice and assessed its potential to mitigate APAP-induced liver injury
Ethics declarations Ethics Approval The experimental procedures conducted in this study adhered to the guidelines set forth by the Committee for the Control and Supervision of Experiments on Animals (CCSEA), Government of India, New Delhi
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