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Acetylcarnitine, on the other hand, affects the epigenetic regulation of metabotropic glutamate type 2 receptors (mGluR2), negatively modulating neurotransmitter release and producing rapid and long-lasting antidepressant effects (demonstrated by forced swim tests, sucrose preference tests) in Flinders Sensitive Line rats and in mice exposed to chronic unpredictable stress, which model genetic and environmentally induced depression, respectively [92]

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Wang, J

TMA (trimethylamine), but not its oxide TMAO (trimethylamine-oxide), exerts haemodynamic effects: implications for interpretation of cardiovascular actions of gut microbiome