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3.3 Molecular mechanisms of supraspinatus atrophy Supraspinatus atrophy in chronic rotator cuff tears (RCTs) results from disrupted protein homeostasis, neuromuscular impairment, inflammation, mitochondrial dysfunction, oxidative stress, and circadian rhythm dysregulation (Krieger et al., 2017)
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A lower mortality in the GLP-1 RA group would expectedly lead to an underestimation of the fracture risk in that group, thereby exaggerating a protective effect of GLP-1 RAs
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