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Cautious use of parenteral cyanocobalamin is also recommended in patients with renal impairment, including premature neonates, because of the possibility of greater aluminum accumulation, which may cause central nervous system and bone toxicity
Results are reviewed before the prescription is transmitted to the pharmacy
After reconstitution, stability depends on the solvent: with Peptide Matrix Water up to 60 days in the refrigerator +2 C to +8 C
Storage conditions (typically 28C, protected from light) and beyond-use dates must follow the sponsor's validated stability data
Stancic-Rokotov D, Balenovic D, Udovicic M, et al
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