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Oxalate induces type II epithelial to mesenchymal transition (EMT) in inner medullary collecting duct cells (IMCD) in vitro and stimulate the expression of osteogenic and fibrotic markers in kidney medulla in vivo

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A single fresh receptor can produce near-maximum output at about 10% engagement, while a normal meal uses only 1% to 4% (receptor saturation). That snapshot does not describe what happens after continuous weekly exposure

doi: 10.1016/j.jaut.2015.04.007 141 Moyron-QuirozJEPartida-SanchezSDonis-HernandezRSandoval-MontesCSantos-ArgumedoL