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These changes occurred without affecting the TRIM37TRIM28 interaction (Fig

Although we cannot rule out a contribution of glycolysis to this ATP increase and did not directly assess the activity of other complexes, we observed increased 5FU sensitivity with inhibitors of ETC complexes IIV, genetic ablation of CI and CIV, and sensitizer genes from CRISPR screening covering additional complexes (CIII and CV)

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The resulting solution was added to S-Trap micros (Protifi) and centrifuged at 4,000 g for 1 min

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