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[1] [2] While high-dose oral B12 supplements can be effective through passive diffusion, they are not routinely recommended for pernicious anaemia management in UK practice
In the cytoplasm, vitamin B12 deficiency impacts the enzyme methionine synthase, with some consequences that adversely affect DNA, RNA, proteins, neurotransmitters, and phospholipids, and with some consequences that indirectly contribute to oxidative stress
"Association between vitamin deficiency and metabolic disorders related to obesity"
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