Patients with pre-existing thyroid conditions should be especially vigilant and may require more frequent thyroid function monitoring during Zepbound therapy
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In contrast, drugs such as Wegovy and Zepbound have shown an ability to produce weight loss almost to a similar extent as bariatric surgery
Choosing between natural pathways, compounded medications, or combination approaches depends on clinical factors: baseline BMI, comorbidities, baseline GLP-1 response biomarkers, and genetic predispositions