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Identifying the links between obesity, insulin resistance and beta-cell function: potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes

Liraglutide administration prevented the decrease of AKT and GSK-3 phosphorylation after treated A 1-42 protein, which inhibiting tau hyperphosphorylation (164, 211)

This compound was further tested in people with type 2 diabetes and, at week 12, plasma glucose and HbA 1c levels decreased significantly from baseline at the highest doses [98]

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