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Enhancement of Glucose-Dependent Insulin Secretion In pancreatic beta cells, GLP-1 increases cyclic AMP (cAMP) levels, activating protein kinase A (PKA) and Epac2 pathways to enhance insulin secretion in a glucose-dependent manner

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doi:10.1016/j.cmet.2022.07.013 Ma J, Hu X, Zhang W, Tao M, Wang M, Lu W