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The integration of these therapies into clinical practice should emphasize individualized decision-making, close monitoring, and combination with behavioral and lifestyle interventions

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This policy is designed as a temporary measure to ensure continuity of care when FDA-approved drugs are not commercially available

Brooks et al., 2022) further contributing to the fatigue and PEM experienced by these patients

13 See FIGURE 1 for a summary of current recommendations from the ADA for second-line therapy in patients with T2DM