For in vitro cytotoxicity assays where benzyl alcohol vehicle effects could confound results, include matched Bacteriostatic Water vehicle controls at the same final benzyl alcohol concentration as the peptide treatment to distinguish compound-specific from vehicle-associated biological effects
d , Relative cell numbers after 72 h of treatment of HCC-1806 cells without or with MK-571 (15 M) in control (208 M cystine
doi:10.1016/j.cca.2008.12.027
We verified the impact of ACTL6A on GSH synthesis and confirmed that ACTL6A KD led to reduced expression of certain genes (GCLC, GPX2, GPX4, SLC7A11, SLC1A5, GSS, GLS, etc.) involved in the GSH synthesis pathway (Supplementary Fig
Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer