Chronic neuroinflammation has been reported to contribute to serotonergic, dopaminergic, and noradrenergic dysfunction in the brain (Song and Wang, 2011) and to lead to chronic immune dysregulation ( Figure 2 Previous studies found that pro-inflammatory cytokines, including tumor necrosis factor- (TNF-) and interleukin (IL)-6, IL-1, and C-reactive protein (CRP), are markedly increased in the blood and CSF of patients with depression (Hestad et al., 2016
Severe diarrhea (more than 6 episodes daily, blood in stool, inability to stay hydrated) warrants medical evaluation, but the solution may be a dose reduction or extended hold at the current dose rather than complete discontinuation
[1] It is prepared in a 30 mL multi-dose vial with a preservative (2 % benzyl alcohol) for multiple withdrawals
As of today, Dividend Yield (TTM)% is 0.56%
Van der Jeugd A, Parra-Damas A, Baeta-Corral R, Soto-Fagus CM, Ahmed T, LaFerla FM, et al