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The treatment significantly improved stool frequency and overall quality of life, compared with a placebo treatment ( Although senna is generally considered safe, it can lead to adverse effects when used for long periods at high dosages

The hallmark symptom is stabbing pain near the heel, particularly intense with the first steps after waking or after prolonged periods of sitting

This is not the drug failing

pasta, couscous, breakfast cereals, crackers, rice, fruit (fresh, tinned, dried), and starchy vegetables such as potatoes, yam and sweet potato

It is generally safe when taken per the recommended dosage, but long-term use should be supervised by medical supervision