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Although the axons remain functional and oligodendrocytes remain active in 12-month-old mice, neuronal viability will likely decline due to reduced ATP and increased production of free radicals, perhaps resulting in degeneration with increasing age (Stahon et al., 2016)
Mertens F, Rydholm A, Bauer HF, Limon J, Nedoszytko B, Szadowska A, et al
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Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity
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