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Digestion: GLP-1 slows gastric emptying, which aids in better nutrient absorption and prevents rapid blood sugar spikes
ATTAIN-2 (NCT05872620) was a Phase III, 72-week, randomized, double-blind, placebo-controlled trial comparing the efficacy and safety of various doses of orforglipron with placebo in adults with obesity or overweight and type 2 diabetes
These molecules modulate gene expression at transcriptional and post-transcriptional levels, influencing inflammation, oxidative stress, and neuronal repair
Significant reductions in subcutaneous fat can alter skin tension, hydration, and barrier function, which may manifest as dryness, sensitivity, or a sensation of tightness
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