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CuCl 2 didnt cause any change in the IL-1, IL-8 and HSPA1A protein levels at the concentration of 58 M, while the protein levels upregulated significantly with 580 M CuCl 2 treatment

These results indicated that TMQ0153 induced intracellular ROS accumulation, DNA damage, and mitochondria-mediated cell death in both AML cell lines, albeit with differences in timing and extent

Nature 622 , 329338 (2023)

The total GAD-7 scores for each participant were categorized into 3 groups, including minimal/mild (total scores 09), moderate (total scores 1014) and severe (total scores 1521) categories (77)