They are an excellent source of protein and B vitamins
Although you may eat plenty of B-12-enriched food, your body may not absorb it or use it efficiently due to aging, alcohol intake, and pollutants from the environment, all of which can take a toll on your body and digestion
Someone with mild symptoms and a gut condition may still need injections, while someone with lower numbers and healthy digestion may respond well to oral B12
High NNMT expression is closely associated with glucose dysregulation: excessive NNMT activation disrupts nicotinamide metabolism, lowers NAD+ levels, impairs insulin signaling, reduces cellular glucose uptake and utilization, and promotes hyperglycemia and insulin resistance
Additionally, some individuals taking Mounjaro may have pre-existing conditions that independently increase their risk of B12 deficiency, such as previous bariatric surgery or concurrent metformin use (the MHRA has highlighted that metformin can reduce vitamin B12 levels)