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Moreover, some clinical trials of the combination of DSF and copper have been completed (NCT00742911 and NCT03034135) or are in progress (NCT04265274, NCT03714555, NCT03363659, and NCT02715609), providing a potential strategy for tumor therapy
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On the other hand, angiogenesis in the CNS is also essential for processes such as embryonic development, recovery from ischemic stroke-type incidents, and recovery from traumatic brain injury (Vallon and Chang 2014)
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