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Oral use of the antifungal ketoconazole has been associated with hepatic toxicity, including some fatalities

Comparative effectiveness of GLP-1 receptor agonists on glycaemic control, body weight, and lipid profile for type 2 diabetes: Systematic review and network meta-analysis

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As GLP-1 Use Expands, Long-Term Safety Questions Remain Under Watch Danielle Valletti, Assistant Editor Kirsty Mackay Key Takeaways A FAERS liver-failure report for newly approved orforglipron underscores challenges separating true drug signals from background incidence, reporting bias, and confounding in early real-world pharmacovigilance