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This reaction is reversible: Under sufficient oxygen availability, lactate can be reconverted into pyruvate by LDHB, which is then subsequently oxidized to acetyl-CoA by pyruvate dehydrogenase (PDH) and enters the tricarboxylic acid cycle (TCA) for efficient energy production (5)

This mechanism aids in reducing the burden of toxins on various organs, particularly the liver, and supports overall cellular health and function

Tejero, J

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Pearsons correlation coefficient was calculated to assess the strength of association between qRT-PCR and RNA-sequencing data