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Oxidative stress induces the dissociation of the NRF2-Keap1 complex When cells undergo oxidative stress, ionizing radiation, or chemical stimulation, it may lead to the generation of reactive oxygen species (ROS) or reactive oxygen free radicals within the cells, triggering an oxidative stress response
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Severe hypoglycemia may result in unconsciousness, coma, seizures, and the inability to swallow and should be treated with glucagon
In addition, more and more studies have proved that such drugs can reduce TC, LDL-C and TG, and increase HDL-C, so as to effectively correct lipid metabolism disorders [129]