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Outcome measures include neurological severity scoring, rotarod and beam walk performance, histological assessment of lesion volume, and immunohistochemistry for axonal markers and myelin basic protein
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In the high-dose group, intracellular glutathione levels increased by 3035% in red blood cells, plasma, and lymphocytes, and by an astonishing 260% in buccal (inner cheek) cells
(7) Complex II: Complex II (succinate dehydrogenase, SDH) is an FAD-dependent enzyme embedded in the mitochondrial inner membrane that oxidizes succinate to fumarate as part of the TCA cycle while transferring the resulting electrons through FAD and a series of ironsulfur clusters to ubiquinone (CoQ 10 ), reducing it to ubiquinol (CoQ 10 H 2 ) 74
