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Standard urine drug tests are designed to identify specific small-molecule substances of abuse such as amphetamines, benzodiazepines, cannabinoids, cocaine, opioids, and phencyclidine

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In addition, the PRO results reported at study endpoint likely do not capture the overall impact of AEs, such as nausea, vomiting and diarrhoea, at the time of the event

Heartburn on tirzepatide affects a meaningful subset of patients and is managed through meal timing and portion size