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Medicare pricing $245/month (government price) $50/month copay for beneficiaries Eligibility: BMI 27 + metabolic risk factor (prediabetes, HTN, etc.) BMI 30 + CKD, HF, uncontrolled BP BMI 35 regardless of comorbidities Medicaid Will also receive reduced pricing Rollout depends on state decision timelines This expands coverage to millions of Americans

High circulating levels of TMAO have been identified as a biomarker associated with an increased risk of cardiovascular disease and systemic inflammation

Genomics 10 , 515526 (1991)

SGLT2 inhibitors Those with breast cancer and type 2 diabetes using SGLT2 saw a 5-year survival rate of 88.9% and a 10-year survival rate of 73.4%

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