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Both L-leucine and creatine were provided at sub-optimal concentrations in the L-Carnitine-combination (2000 mg and 3000 mg, respectively) than what is recommended for these supplements to optimally increase muscle mass (reviewed in [43])
GPX14 and GPX6 are seleniumcontaining protein, but GPX5 does not contain selenocysteine or Se in active site [41, 42]
Clinical trials 76,77,78 have focused primarily on improving the left ventricular ejection fraction (LVEF), which is attributed to the ability of NRG1 to increase sarcoplasmic reticular calcium reuptake and reduce cardiomyocyte stiffness
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