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Metabolic byproducts shift pH, which accelerates deamidation at Asn and Gln residues
An early analysis of the results of 12 randomized controlled trials showed that folic acid supplementation (0.5-5 mg/day) had the greatest lowering effect on blood homocysteine concentrations (25% decrease)
Methylamines are another subset of microbial-derived metabolites that are produced by the microbial metabolism of choline and L-carnitine
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