This powerhouse ingredient has been quietly revolutionising how we think about cleansing and skin health
For OCTN2, D139N is a variant potentially associated with SPCD that does localise correctly to the membrane, but does not impair transport activity in uptake assays 11
Similarly, AARS2 has been found to regulate cell metabolism through lactylation, specifically by limiting the influx of acetyl-CoA in pyruvate and fatty acid oxidation processes, ultimately inhibiting oxidative phosphorylation [81]
Avoid mixing with incompatible ingredients: GHK-Cu works well with hydrating and antioxidant ingredients but may be less stable when combined with high concentrations of vitamin C or niacinamide
Complementary Ingredients Superior formulas include Sulforaphane (enhances glutathione activity), Milk thistle (supports liver detox) or N-acetylcysteine (a precursor of cysteine and, thereby, glutathione)