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10 Cellular outcome of SLC33A1 loss in mammalian cells

Craig LB, Brush RS, Sullivan MT, Zavy MT, Agbaga MP, Anderson RE

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244 Conclusions and future perspectives Once inside a cell, cysteine can have different fates, including the synthesis of glutathione or proteins, oxidative or non-oxidative catabolism, and reversible post-translational protein modification, each of which can contribute to the development and progression of cancer (Fig