melanotic macule

melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Pathology Outlines - Melanotic macule

Name: melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Pathology Outlines - Melanotic macule
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SKU: 13366614901
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SKU: 13366614901

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284 A similar phenomenon has been observed in Gln-dependent clear cell renal carcinoma (RCC), which competitively depletes environmental Gln, causing local Gln depletion and IL-23 release from tumor-infiltrating macrophages, which further activates Treg function to suppress tumor immunity

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